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2004 1
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2009 4
2010 1
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2023 1
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Page 1
Interaction between smoking and PON2 Ser311Cys polymorphism as a determinant of the risk of myocardial infarction.
Martinelli N, Girelli D, Olivieri O, Stranieri C, Trabetti E, Pizzolo F, Friso S, Tenuti I, Cheng S, Grow MA, Pignatti PF, Corrocher R. Martinelli N, et al. Eur J Clin Invest. 2004 Jan;34(1):14-20. doi: 10.1111/j.1365-2362.2004.01292.x. Eur J Clin Invest. 2004. PMID: 14984433
The adjusted OR for MI among PON2 311Cys carriers was 1.5 (95%CI, 1.03-2.19). A gene-environmental interaction was found between PON2 Ser311Cys and smoking. ...The PON2 polymorphism did not influence the MI risk among nonsmokers. ...
The adjusted OR for MI among PON2 311Cys carriers was 1.5 (95%CI, 1.03-2.19). A gene-environmental interaction was found between P …
Mechanistic insights and perspectives involved in neuroprotective action of quercetin.
Grewal AK, Singh TG, Sharma D, Sharma V, Singh M, Rahman MH, Najda A, Walasek-Janusz M, Kamel M, Albadrani GM, Akhtar MF, Saleem A, Abdel-Daim MM. Grewal AK, et al. Biomed Pharmacother. 2021 Aug;140:111729. doi: 10.1016/j.biopha.2021.111729. Epub 2021 May 25. Biomed Pharmacother. 2021. PMID: 34044274 Free article. Review.
This review assesses the food sources of quercetin, its pharmacokinetic profile, structure activity relationship and its pathophysiological role in various NDDs and it also provides a synopsis of the literature exploring the relationship between quercetin and various downstream s …
This review assesses the food sources of quercetin, its pharmacokinetic profile, structure activity relationship and its pathophysiological …
MicroRNA-423 may regulate diabetic vasculopathy.
Blum A, Meerson A, Rohana H, Jabaly H, Nahul N, Celesh D, Romanenko O, Tamir S. Blum A, et al. Clin Exp Med. 2019 Nov;19(4):469-477. doi: 10.1007/s10238-019-00573-8. Epub 2019 Aug 17. Clin Exp Med. 2019. PMID: 31422516
Additionally, the mRNA levels of endothelial nitric oxide synthase (eNOS), induced NOS (iNOS), C reactive protein (CRP), VEGF, tumor necrosis factor alpha (TNFalpha), PON2, p22, and SOD2 were measured in human vascular endothelial cells cultured in the presence of p …
Additionally, the mRNA levels of endothelial nitric oxide synthase (eNOS), induced NOS (iNOS), C reactive protein (CRP), VEGF, tumor necr …
Exploring the role of paraoxonases in the pathogenesis of coronary artery disease: a systematic review.
Abelló D, Sancho E, Camps J, Joven J. Abelló D, et al. Int J Mol Sci. 2014 Nov 14;15(11):20997-1010. doi: 10.3390/ijms151120997. Int J Mol Sci. 2014. PMID: 25405733 Free PMC article. Review.
Paraoxonases (PON) are three enzymes (PON1, PON2 and PON3) that play a role in the organism's antioxidant system; alterations in which are associated with diseases involving oxidative stress. ...The relationship between PON gene polymorphisms and CAD was not conclusive, bu …
Paraoxonases (PON) are three enzymes (PON1, PON2 and PON3) that play a role in the organism's antioxidant system; alterations in whic …
PON1 Hypermethylation and PON3 Hypomethylation are Associated with Risk of Cerebral Infarction.
Xiao J, Li X, Yuan Q, Zhang S, Qu K, Wu B, Wang Y, Duan S. Xiao J, et al. Curr Neurovasc Res. 2019;16(2):115-122. doi: 10.2174/1567202616666190412154407. Curr Neurovasc Res. 2019. PMID: 30977447
The quantitative methylation-specific PCR (qMSP) was used to determine the promoter methylation levels of PON1, PON2 and PON3 genes. The methylation level was expressed as a methylation reference percentage (PMR). ...On the contrary, PON3 methylation was significantly lowe …
The quantitative methylation-specific PCR (qMSP) was used to determine the promoter methylation levels of PON1, PON2 and PON3 genes. …
Trailing TRAIL Resistance in Human Breast Adenocarcinoma Cells with Trichostatin A and Zebularine.
Wong SHM, Fang CM, Loh HS, Ngai SC. Wong SHM, et al. Anticancer Agents Med Chem. 2023;23(7):817-831. doi: 10.2174/1871520623666221114095733. Anticancer Agents Med Chem. 2023. PMID: 36380402
AIMS: The aim of this study was to sensitize the resistant breast adenocarcinoma cells towards Tumour Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced apoptosis. ...For E-MDA-MB- 231, down-regulation of catalase, paraoxonase-2 (PON2), clusterin, an …
AIMS: The aim of this study was to sensitize the resistant breast adenocarcinoma cells towards Tumour Necrosis Factor-related Apoptos …
Metabolomic Identification of Anticancer Metabolites of Australian Propolis and Proteomic Elucidation of Its Synergistic Mechanisms with Doxorubicin in the MCF7 Cells.
Alsherbiny MA, Bhuyan DJ, Radwan I, Chang D, Li CG. Alsherbiny MA, et al. Int J Mol Sci. 2021 Jul 22;22(15):7840. doi: 10.3390/ijms22157840. Int J Mol Sci. 2021. PMID: 34360606 Free PMC article.

AP-1 significantly enhanced the inhibitory effect of DOX against MCF7 cell proliferation in a dose-dependent manner with significant inhibition of the reactive oxygen species (p < 0.0001) compared to DOX alone. AP-1 enabled the reversal of DOX-mediated necrosis to progr

…
AP-1 significantly enhanced the inhibitory effect of DOX against MCF7 cell proliferation in a dose-dependent manner with significant inhibit …
The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.
Gluba A, Pietrucha T, Banach M, Piotrowski G, Rysz J. Gluba A, et al. Angiology. 2010 Feb;61(2):157-65. doi: 10.1177/0003319709351258. Epub 2009 Nov 24. Angiology. 2010. PMID: 19939821
We evaluated the influence of 2 polymorphisms within PON1 (192 Gln/ Arg) and PON2 (311 Ser/Cys) genes in 407 young Poles: 273 patients who experienced a first myocardial infarction (MI) under the age of 45 (study group) and 134 healthy volunteers (control group) with a HEA …
We evaluated the influence of 2 polymorphisms within PON1 (192 Gln/ Arg) and PON2 (311 Ser/Cys) genes in 407 young Poles: 273 patient …
Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway.
Sulaiman D, Li J, Devarajan A, Cunningham CM, Li M, Fishbein GA, Fogelman AM, Eghbali M, Reddy ST. Sulaiman D, et al. J Mol Cell Cardiol. 2019 Apr;129:154-164. doi: 10.1016/j.yjmcc.2019.02.008. Epub 2019 Feb 23. J Mol Cell Cardiol. 2019. PMID: 30802459
RESULTS: PON2 gene expression is upregulated in WT mice following in vivo IRI. ...PON2 knockdown in H9c2 cells subjected to HRI leads to an increase in mitochondrial membrane depolarization. ...
RESULTS: PON2 gene expression is upregulated in WT mice following in vivo IRI. ...PON2 knockdown in H9c2 cells subjected to HR …
Effect of sub-toxic exposure to Malathion on glucose uptake and insulin signaling in L6 myoblast derived myotubes.
Shrestha S, Kumar Singh V, Kumar Sarkar S, Shanmugasundaram B, Jeevaratnam K, Chandra Koner B. Shrestha S, et al. Drug Chem Toxicol. 2020 Nov;43(6):663-670. doi: 10.1080/01480545.2018.1531881. Epub 2018 Nov 29. Drug Chem Toxicol. 2020. PMID: 30486685
Paraoxonase (PON) activity was measured in cell lysate using p-nitrophenyl acetate as substrate. PON1 and PON2 expression in myotubes were assessed by PCR. The glucose uptake and total antioxidant level in L6-derived myotubes after sub-toxic exposure to Malathion were decr …
Paraoxonase (PON) activity was measured in cell lysate using p-nitrophenyl acetate as substrate. PON1 and PON2 expression in myotubes …
20 results